Article
Survival of BRCA1/BRCA2-associated pT1 breast cancer patients, a cohort study.
Breast cancer research and treatment - 1 Jul 2022
van Barele Mark, Rieborn Amy, Heemskerk-Gerritsen Bernadette A M, Obdeijn Inge-Marie, Koppert Linetta B, Loo Claudette E, Tollenaar Rob A E M, Ausems Margreet G E M, van de Beek Irma, Berger Lieke P V, de Boer Maaike, van Hest Liselot P, Kets C Marleen, Rookus Matti, Schmidt Marjanka K, Jager Agnes, Hooning Maartje J
Abstract excerpt
PURPOSE: Intensive screening in BRCA1/2 mutation carriers aims to improve breast cancer (BC) prognosis. Our aim is to clarify the prognostic impact of tumor size in BRCA mutation carriers with a pT1 BC, which is currently unclear. We are especially interested in differences between pT1a, pT1b, and pT1c regarding the prognosis of node-negative breast cancer, the effect of chemotherapy, and the prevalence of lymph...
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