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Article

MYH7 variants cause complex congenital heart disease.

American journal of medical genetics. Part A - 1 Sept 2022

Ritter Alyssa, Leonard Jacqueline, Gray Christopher, Izumi Kosuke, Levinson Katharine, Nair Divya R, O'Connor Matthew, Rossano Joseph, Shankar Venkat, Chowns Jessica, Marzolf Amy, Owens Anjali, Ahrens-Nicklas Rebecca C

Abstract excerpt

MYH7, encoding the myosin heavy chain sarcomeric β-myosin heavy chain, is a common cause of both hypertrophic and dilated cardiomyopathy. Additionally, families with left ventricular noncompaction cardiomyopathy (LVNC) and congenital heart disease (CHD), typically septal defects or Ebstein anomaly, have been identified to have heterozygous pathogenic variants in MHY7. One previous case of single ventricle CHD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35491958
DOI: 10.1002/ajmg.a.62766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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MYH7 variants cause complex congenital heart disease.PMID 35491958Read ↗

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