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Recurrent copy number alterations involving EGFR , CDKN2A , and CCND1 in oral premalignant lesions

30 Apr 2022

Abstract excerpt

BACKGROUND: A major challenge in the management of patients with oral leukoplakia is the difficulty to identify patients at high risk of developing oral squamous cell carcinoma. Our knowledge about genomic alterations in oral leukoplakia, and in particular those that progress to oral squamous cell carcinoma, is scarce and there are no useful biomarkers that can predict the risk of malignant transformation....

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PMID: 35488777
DOI: 10.1111/jop.13303

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