Article
Alport syndrome and autosomal dominant tubulointerstitial kidney disease frequently underlie end-stage renal disease of unknown origin-a single-center analysis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 22 Sept 2022
Leenen Esther, Erger Florian, Altmüller Janine, Wenzel Andrea, Thiele Holger, Harth Ana, Tschernoster Nikolai, Lokhande Shanti, Joerres Achim, Becker Jan-Ulrich, Ekici Arif, Huettel Bruno, Beck Bodo, Weidemann Alexander
Abstract excerpt
BACKGROUND: The prevalence of end-stage renal disease of unknown etiology in adult patients is globally high and accounts for almost 20% of all dialysis patients. Recent studies have suggested that the percentage of adult patients with a causal genetic variant has been underestimated so far. Despite severe prognostic and therapeutic implications, awareness about prevalence and manifestations of genetic kidney...
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