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Cell‐free DNA as a biomarker after lung transplantation: A proof‐of‐concept study

19 Apr 2022

Abstract excerpt

BACKGROUND: Lung transplantation (LTx) is a lifesaving procedure burdened with limited long-term survival. The most common cause of death after LTx is chronic lung allograft dysfunction (CLAD). Today, useful biomarkers for the detection of CLAD are lacking. Circulating cell-free DNA (cfDNA) is released during cellular decay and can be detected using polymerase chain reaction (PCR). Thus, donor-derived cfDNA in...

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PMID: 35478446
DOI: 10.1002/iid3.620

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