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Article

Within-Host Genetic Variation in Neisseria gonorrhoeae over the Course of Infection.

Microbiology spectrum - 29 Jun 2022

de Korne-Elenbaas Jolinda, Bruisten Sylvia M, de Vries Henry J C, van Dam Alje P

Abstract excerpt

Knowledge of within-host genetic variation informs studies on transmission dynamics. We studied within-host genetic variation in Neisseria gonorrhoeae over the course of infection and across different anatomical locations. Isolates were obtained during a clinical trial, and isolates from consecutive time points reflected persistent infections after treatment failure. We compared sequence types (STs) and...

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Identifiers

PMID: 35467402
DOI: 10.1128/spectrum.00313-22
PMCID: PMC9241688

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