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Heterogeneity of the tumor immune microenvironment and its clinical relevance

23 Apr 2022

Abstract excerpt

During the course of tumorigenesis and subsequent metastasis, malignant cells gradually diversify and become more heterogeneous. Consequently, the tumor mass might be infiltrated by diverse immune-related components, including the cytokine/chemokine environment, cytotoxic activity, or immunosuppressive elements. This immunological heterogeneity is universally presented spatially or varies temporally along with...

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PMID: 35461288
DOI: 10.1186/s40164-022-00277-y

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