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The Notch signaling network in muscle stem cells during development, homeostasis, and disease

22 Apr 2022

Abstract excerpt

Skeletal muscle stem cells have a central role in muscle growth and regeneration. They reside as quiescent cells in resting muscle and in response to damage they transiently amplify and fuse to produce new myofibers or self-renew to replenish the stem cell pool. A signaling pathway that is critical in the regulation of all these processes is Notch. Despite the major differences in the anatomical and cellular...

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PMID: 35459219
DOI: 10.1186/s13395-022-00293-w

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