Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

B-cell lymphoma-2 downregulation is a useful feature supporting a neoplastic phenotype in mature T-cell lymphomas.

Human pathology - 1 Jul 2022

Siddiqui Faiza, Perez Silos Vanessa, Karube Kennosuke, Yasin Goksu Suleyman, Nandakumar Srinath, Saygin Caner, Onajin Oluwakemi, Prabu Swetha S, Gurbuxani Sandeep, Arber Daniel A, Tjota Melissa, Segal Jeremy, Smith Sonali M, Murga-Zamalloa Carlos A, Venkataraman Girish

Abstract excerpt

Normal T cells express high levels of B-cell lymphoma-2 (BCL2) protein, and data regarding BCL2 expression status and its diagnostic utility in T-cell lymphoma are scarce. We evaluated BCL2 expression in a series of mature T-cell lymphoproliferations (TCLs) including indolent and more recently recognized entities (follicular helper T-cell [TFH] lymphomas). Sixty-six neoplastic biopsies (60 patients) representing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Down-Regulation
Share to Leukemia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lymphoma, B-Cell

Share to Lymphoma, T-Cell

Share to Lymphoma, T-Cell, Peripheral

Share to Phenotype

Share to Proto-Oncogene Proteins c-bcl-2

Source

Identifiers

PMID: 35452696
DOI: 10.1016/j.humpath.2022.04.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

B-cell lymphoma-2 downregulation is a useful feature supporting a neoplastic phenotype in mature T-cell lymphomas.PMID 35452696Read ↗

The expanding spectrum of T-cell lymphomas with follicular helper T-cell phenotype and implications for differential diagnoses: A report of the 2023 SH/EA4HP Lymphoma Workshop.Semantic proximity Read ↗

Pathology of B-cell lymphomas: diagnosis and biomarker discovery.Semantic proximity Read ↗

T-cell Lymphomas: Updates in Biology and Diagnosis.Semantic proximity Read ↗

New insights into the biology of T-cell lymphomasSemantic proximity Read ↗

Challenges in nodal peripheral T-cell lymphomas: from biological advances to clinical applicabilitySemantic proximity Read ↗

Mutational Landscape of TdT+ Large B-cell Lymphomas Supports Their Distinction From B-lymphoblastic Neoplasms: A Multiparameter Study of a Rare and Aggressive Entity.Semantic proximity Read ↗

Advances in peripheral T cell lymphomas: pathogenesis, genetic landscapes and emerging therapeutic targetsSemantic proximity Read ↗

Clinicopathological features of adult T-cell leukemia/lymphoma with T-follicular helper phenotype.Semantic proximity Read ↗

Pathology of peripheral T-cell lymphomas: where do we stand?Semantic proximity Read ↗

Tumor heterogeneity and immune-evasive T follicular cell lymphoma phenotypes at single-cell resolution.Semantic proximity Read ↗

Novel insights into the pathogenesis of T-cell lymphomasSemantic proximity Read ↗

Marginal Zone Lymphoma With T-Follicular Helper Hyperplasia: Paving the Way for New Concepts in Cellular Plasticity and Unveiling Histopathologic Pitfalls.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.