Article
[Association between genetic predisposition to childhood obesity and the risk of adult ischemic heart disease in China].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 10 Apr 2022
Wang W X, Huang N H, Lyu J, Yu C Q, Guo Y, Pei P, Du H D, Chen J S, Chen Z M, Huang T, Li Liming
Abstract excerpt
Objective: To examine the associations of childhood obesity, assessed by genetic variations of childhood body mass index (BMI), with the risk of adult ischemic heart disease (IHD) and major coronary event (MCE). Methods: More than 69 000 participants from the China Kadoorie Biobank were genotyped. After excluding those with coronary heart disease, stroke, or cancer at baseline, a total of 64 454 participants were...
Topics
- Adult
- Body Mass Index
- Child
- China
- Genetic Predisposition to Disease
- Humans
- Myocardial Ischemia
- Pediatric Obesity
- Prospective Studies
- Risk Factors