Gut Microbiome Signature Are Correlated With Bone Mineral Density Alterations in the Chinese Elders

Abstract excerpt

Objective Osteoporosis (OP), clinically featured with a low bone mineral density (BMD) and high risk of bone fracture, has become a major risk factor of disability and death in the elders, especially in postmenopausal women. The gut microbiome (GM) is thought to be implicated in bone metabolism. Herein, we clarified the composition signature and gene functional profile of GM in older people with normal and low...

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