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Article

Impact of 16S rRNA Single Nucleotide Polymorphisms on Mycoplasma genitalium Organism Load with Doxycycline Treatment.

Antimicrobial agents and chemotherapy - 17 May 2022

Chua Teck-Phui, Danielewski Jennifer, Bodiyabadu Kaveesha, Bradshaw Catriona S, Machalek Dorothy A, Garland Suzanne M, Plummer Erica L, Vodstrcil Lenka A, Murray Gerald L

Abstract excerpt

Doxycycline targets the 16S rRNA and is widely used for the treatment of sexually transmitted infections. While it is not highly effective at eradicating Mycoplasma genitalium infections, it can reduce organism load. The aim of this study was to investigate the association between single nucleotide polymorphisms (SNPs) in the 16S rRNA gene of M. genitalium and change in organism load. M. genitalium samples were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35420491
DOI: 10.1128/aac.00243-22
PMCID: PMC9112994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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