Phenotypic and HLA-DRB1 allele characterization of Swedish cardiac sarcoidosis patients.

doi:10.1016/j.ijcard.2022.04.006

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Article

Phenotypic and HLA-DRB1 allele characterization of Swedish cardiac sarcoidosis patients.

International journal of cardiology - 15 Jul 2022

Eldhagen Per, Bobbio Emanuele, Darlington Pernilla, Grunewald Johan, Eklund Anders, Polte Christian L, Bergh Niklas, Bollano Entela, Sörensson Peder, Kullberg Susanna

Abstract excerpt

BACKGROUND: Early detection and initiation of treatment in cardiac sarcoidosis (CS) is believed to be crucial to reduce morbidity and mortality. The diagnosis of CS is challenging, especially in isolated CS (ICS). Certain human leukocyte antigen (HLA-DRB1) alleles associate with different phenotypes of sarcoidosis. Phenotypic and genotypic characterization of patients with CS may improve our ability to identify...

Topics

Alleles
Female
HLA-DRB1 Chains
Humans
Male
Myocarditis
Phenotype
Sarcoidosis
Stroke Volume
Sweden
Ventricular Function, Left

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Open in PubMed

Identifiers

PMID: 35395284
DOI: 10.1016/j.ijcard.2022.04.006

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