Article
Coexistence of cardiac sarcoidosis and arrhythmogenic cardiomyopathy-associated genetic variants: a multicentre case-control study.
Heart (British Cardiac Society) - 2 May 2025
Rossi Valentina Alice, Palazzini Matteo, Ammirati Enrico, Gasperetti Alessio, Grubler Martin, Brunckhorst Corinna, Manka Robert, Giannopoulos Andreas, Tanner Felix C, Medeiros-Domingo Argelia, Gentile Piero, Bramerio Manuela, Schmidt Dörthe, Tondo Claudio, Flammer Andreas J, Ruschitzka Frank, Duru Firat, Saguner Ardan Muammer
Abstract excerpt
BACKGROUND: Cardiac sarcoidosis (CS) is a chronic inflammatory disease characterised by non-caseating granulomas, while arrhythmogenic cardiomyopathy (ACM) is a genetic condition mainly affecting desmosomal proteins. The coexistence of CS and genetic variants associated with ACM is not well understood, creating challenges in diagnosis and management. This study aimed to describe the clinical, imaging and genetic...
Read the complete abstract on PubMedTopics
- Humans
- Sarcoidosis
- Male
- Female
- Middle Aged