Article
Gastrointestinal stromal tumors with Kit gene mutation in 4 guinea pigs (Cavia porcellus).
Veterinary pathology - 1 Sept 2022
Ueda Kengo, Takanosu Masamine, Kagawa Yumiko, Ueda Akiko, Ano Naoko, Nomura Kohji, Ozaki Kiyokazu
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) have been rarely reported in guinea pigs. We aimed to characterize the clinical and pathological features of GISTs in 4 guinea pigs and investigate the presence of mutations in exon 11 of the KIT proto-oncogene receptor tyrosine kinase (Kit) gene. Two subjects were male and 2 were female; 2 were 6 years old, 1 was 7 years old, and 1 was of an unknown age. Three cases had...
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