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SARS-CoV-2 Mutations and COVID-19 Clinical Outcome: Mutation Global Frequency Dynamics and Structural Modulation Hold the Key.

Frontiers in cellular and infection microbiology - 1 Jan 2022

Maurya Ranjeet, Mishra Pallavi, Swaminathan Aparna, Ravi Varsha, Saifi Sheeba, Kanakan Akshay, Mehta Priyanka, Devi Priti, Praveen Shaista, Budhiraja Sandeep, Tarai Bansidhar, Sharma Shimpa, Khyalappa Rajesh J, Joshi Meghnad G, Pandey Rajesh

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had an enormous burden on the healthcare system worldwide as a consequence of its new emerging variants of concern (VOCs) since late 2019. Elucidating viral genome characteristics and its influence on disease severity and clinical outcome has been one of the crucial aspects toward pandemic management. Genomic surveillance holds the key to identify...

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Identifiers

PMID: 35386683
DOI: 10.3389/fcimb.2022.868414
PMCID: PMC8978958

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