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Article

Sevoflurane inhibits the malignant phenotypes of glioma through regulating miR-146b-5p/NFIB axis.

Metabolic brain disease - 1 Jun 2022

Wang Haili, Cheng Guofang, Quan Lili, Qu Haibo, Yang Ailing, Ye Jiangge, Feng Yuanbo, Li Xiaofang, Shi Xiaoli, Pan Hua

Abstract excerpt

PURPOSE: Sevoflurane is a common used inhaled anesthetic that was reported to regulate the progression of multiple cancers. Here, we aimed to investigate the function and regulatory mechanism underlying sevoflurane in glioma cells. METHODS: A172 and U251 cells were treated with different concentrations of sevoflurane. Colony formation, EdU satining and 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium...

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Identifiers

PMID: 35386035
DOI: 10.1007/s11011-022-00959-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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