Article
Natural History of Type II Autosomal Dominant Osteopetrosis: A Single Center Retrospective Study.
Frontiers in endocrinology - 1 Jan 2022
Wang Ziyuan, Li Xiang, Wang Ya, Fu Wenzhen, Liu Yujuan, Zhang Zhenlin, Wang Chun
Abstract excerpt
Background: Autosomal dominant osteopetrosis II (ADO II, MIM166600) is a sclerosing bone disorder caused by CLCN7 mutation. The main clinical characteristics include minor trauma-related fracture and hip osteoarthritis, whereas cranial nerve palsy and bone marrow failure rarely develop. Although it is generally believed that ADO II has a relatively benign course, the natural course of the disease in Chinese...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.