Clinical utility of comprehensive genomic profiling in Japan: Result of PROFILE-F study.

doi:10.1371/journal.pone.0266112

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Clinical utility of comprehensive genomic profiling in Japan: Result of PROFILE-F study.

PloS one - 1 Jan 2022

Aoyagi Yasuko, Kano Yoshihito, Tohyama Kohki, Matsudera Shotaro, Kumaki Yuichi, Takahashi Kenta, Mitsumura Takahiro, Harada Yohei, Sato Akemi, Nakamura Hideaki, Sueoka Eisaburo, Aragane Naoko, Kimura Koichiro, Onishi Iichiro, Takemoto Akira, Akahoshi Keiichi, Ono Hiroaki, Ishikawa Toshiaki, Tokunaga Masanori, Nakagawa Tsuyoshi, Oshima Noriko, Nakamura Reiko, Takagi Masatoshi, Asakage Takahiro, Uetake Hiroyuki, Tanabe Minoru, Miyake Satoshi, Kinugasa Yusuke, Ikeda Sadakatsu

Abstract excerpt

INTRODUCTION: Clinical sequencing has provided molecular and therapeutic insights into the field of clinical oncology. However, despite its significance, its clinical utility in Japanese patients remains unknown. Here, we examined the clinical utility of tissue-based clinical sequencing with FoundationOne® CDx and FoundationOne® Heme. Between August 2018 and August 2019, 130 Japanese pretreated patients with...

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PMID: 35358259
DOI: 10.1371/journal.pone.0266112
PMCID: PMC8970371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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