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Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach

25 Mar 2022

Abstract excerpt

BACKGROUND: The response rates of the clinical chemotherapies are still low in clear cell renal cell carcinoma (ccRCC). Computational drug repositioning is a promising strategy to discover new uses for existing drugs to treat patients who cannot get benefits from clinical drugs. METHODS: We proposed a systematic approach which included the target prediction based on the co-expression network analysis of...

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PMID: 35339898
DOI: 10.1016/j.ebiom.2022.103963

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