Article
Artificial Intelligence-Powered Hematoxylin and Eosin Analyzer Reveals Distinct Immunologic and Mutational Profiles among Immune Phenotypes in Non-Small-Cell Lung Cancer.
The American journal of pathology - 1 Apr 2022
Park Jonghanne, Cho Hyung-Gyo, Park Jewel, Lee Grace, Kim Hye Sung, Paeng Kyunghyun, Song Sanghoon, Park Gahee, Ock Chan-Young, Chae Young Kwang
Abstract excerpt
The tumor microenvironment can be classified into three immune phenotypes: inflamed, immune excluded, and immune-desert. Immunotherapy efficacy has been shown to vary by phenotype; yet, the mechanisms are poorly understood and demand further investigation. This study unveils the mechanisms using an artificial intelligence-powered software called Lunit SCOPE. Artificial intelligence was used to classify 965...
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