Article
Integration of multiparameter flow cytometry score improves prognostic stratification provided by standard models in primary myelofibrosis.
American journal of hematology - 1 Jul 2022
Mannelli Francesco, Bencini Sara, Coltro Giacomo, Loscocco Giuseppe G, Peruzzi Benedetta, Rotunno Giada, Maccari Chiara, Gesullo Francesca, Borella Miriam, Paoli Chiara, Caporale Roberto, Mannarelli Carmela, Annunziato Francesco, Guglielmelli Paola, Vannucchi Alessandro M
Abstract excerpt
Prognostic modeling in myelofibrosis (MF) has classically pursued the integration of informative clinical and hematological parameters to separate patients' categories with different outcomes. Modern stratification includes also genetic data from karyotype and mutations. However, some poorly standardized variables, as peripheral blood (PB) blast count by morphology, are still included. In this study, we used...
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