MIPSS70: Mutation-Enhanced International Prognostic Score System for Transplantation-Age Patients With Primary Myelofibrosis.

doi:10.1200/JCO.2017.76.4886

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Article

MIPSS70: Mutation-Enhanced International Prognostic Score System for Transplantation-Age Patients With Primary Myelofibrosis.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Feb 2018

Guglielmelli Paola, Lasho Terra L, Rotunno Giada, Mudireddy Mythri, Mannarelli Carmela, Nicolosi Maura, Pacilli Annalisa, Pardanani Animesh, Rumi Elisa, Rosti Vittorio, Hanson Curtis A, Mannelli Francesco, Ketterling Rhett P, Gangat Naseema, Rambaldi Alessandro, Passamonti Francesco, Barosi Giovanni, Barbui Tiziano, Cazzola Mario, Vannucchi Alessandro M, Tefferi Ayalew

Abstract excerpt

Purpose To develop a prognostic system for transplantation-age patients with primary myelofibrosis (PMF) that integrates clinical, cytogenetic, and mutation data. Patients and Methods The study included 805 patients with PMF age ≤ 70 years recruited from multiple Italian centers and the Mayo Clinic (Rochester, MN), forming two independent learning and validation cohorts. A Cox multivariable model was used to...

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PMID: 29226763
DOI: 10.1200/JCO.2017.76.4886

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ASXL1
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