Major Histocompatibility Complex Class II HLA-DRB1 Allelic Epitopes in Fibromyalgia.

doi:10.2174/2772270816666220321162802

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Article

Major Histocompatibility Complex Class II HLA-DRB1 Allelic Epitopes in Fibromyalgia.

Recent advances in inflammation & allergy drug discovery - 1 Jan 2022

Puri Basant K, Lee Gary S, Schwarzbach Armin

Abstract excerpt

BACKGROUND: Preliminary evidence has pointed an association of the gene HLA-DRB1 with fibromyalgia. HLA-DRB1 alleles carrying the shared or susceptibility epitope encoding the five-amino acid motif QKRAA, QRRAA or RRRAA in positions 70 to 74 of the major histocompatibility complex class II DRβ chain are associated with several autoimmune diseases. OBJECTIVE: The objective of this study was to test the hypothesis...

Topics

Humans
Arthritis, Rheumatoid
Epitopes
Fibromyalgia
Genetic Predisposition to Disease
HLA-DRB1 Chains
Major Histocompatibility Complex

Source

Open in PubMed

Identifiers

PMID: 35319406
DOI: 10.2174/2772270816666220321162802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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