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Article

Evaluation of vitamin D receptor gene polymorphisms (ApaI and TaqI) as risk factors of vitiligo and predictors of response to narrowband UVB phototherapy.

Archives of dermatological research - 1 Apr 2023

Youssef Youssef Elbayoumy, Eldegla Heba Elsayed Abdelmoneim, Elmekkawy Rana Samir Mahmoud, Gaballah Mohammad Ali

Abstract excerpt

Vitiligo is acquired depigmentation due to multiple factors. Vitamin D in skin, through its receptors (VDR), regulates cell growth, differentiation, immune response and exerts both stimulatory and protective effects on melanocytes. The gene sequence encoding VDR has polymorphic forms such as ApaI and TaqI that may affect vitamin D actions. Narrowband ultraviolet B (NB-UVB) phototherapy became the mainstay of...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35318513
DOI: 10.1007/s00403-022-02348-w
PMCID: PMC10020320

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