Article
Analysis of SARS-CoV-2 variants B.1.617: host tropism, proteolytic activation, cell-cell fusion, and neutralization sensitivity.
Emerging microbes & infections - 1 Dec 2022
Zhang Li, Li Qianqian, Wu Jiajing, Yu Yuanling, Zhang Yue, Nie Jianhui, Liang Ziteng, Cui Zhimin, Liu Shuo, Wang Haixin, Ding Ruxia, Jiang Fei, Li Tao, Nie Lingling, Lu Qiong, Li Jiayi, Qin Lili, Jiang Yinan, Shi Yi, Xu Wenbo, Huang Weijin, Wang Youchun
Abstract excerpt
SARS-CoV-2 has caused the COVID-19 pandemic. B.1.617 variants (including Kappa and Delta) have been transmitted rapidly in India. The transmissibility, pathogenicity, and neutralization characteristics of these variants have received considerable interest. In this study, 22 pseudotyped viruses were constructed for B.1.617 variants and their corresponding single amino acid mutations. B.1.617 variants did not...
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