Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Engineering stem cells to produce exosomes with enhanced bone regeneration effects: an alternative strategy for gene therapy

15 Mar 2022

Abstract excerpt

BACKGROUND: Exosomes derived from stem cells have been widely studied for promoting regeneration and reconstruction of multiple tissues as "cell-free" therapies. However, the applications of exosomes have been hindered by limited sources and insufficient therapeutic potency. RESULTS: In this study, a stem cell-mediated gene therapy strategy is developed in which mediator mesenchymal stem cells are genetically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Tissue Engineering Materials
Share to Extracellular vesicles in disease
Share to Mesenchymal stem cell research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35292020
DOI: 10.1186/s12951-022-01347-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Engineering stem cells to produce exosomes with enhanced bone regeneration effects: an alternative strategy for gene therapyPMID 35292020Read ↗

Potential applications of mesenchymal stem cells and their derived exosomes in regenerative medicineSemantic proximity Read ↗

Mesenchymal Stem Cell-Derived Exosomes and MicroRNAs in Cartilage Regeneration: Biogenesis, Efficacy, miRNA Enrichment and DeliverySemantic proximity Read ↗

A Role for Exosomes in Craniofacial Tissue Engineering and RegenerationSemantic proximity Read ↗

Exosomes Derived from Mesenchymal Stem CellsSemantic proximity Read ↗

Engineering Stem Cells for Biomedical ApplicationsSemantic proximity Read ↗

Adipose-derived stem cell exosomes promote critical-sized bone defect repair by enhancing the homing of bone marrow mesenchymal stem cellsSemantic proximity Read ↗

Unlocking the potential of exosomes: a breakthrough in the theranosis of degenerative orthopaedic diseasesSemantic proximity Read ↗

Mesenchymal stem/stromal cells as a delivery platform in cell and gene therapiesSemantic proximity Read ↗

The role and mechanism of exosomes from umbilical cord mesenchymal stem cells in inducing osteogenesis and preventing osteoporosisSemantic proximity Read ↗

The effects of exosomes originating from different cell sources on the differentiation of bone marrow mesenchymal stem cells into Schwann cellsSemantic proximity Read ↗

Enhancing Cartilage Repair: Surgical Approaches, Orthobiologics, and the Promise of ExosomesSemantic proximity Read ↗

Mesenchymal stem cell exosomesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.