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Enhanced Transmissibility and Decreased Virulence of HIV-1 CRF07_BC May Explain Its Rapid Expansion in China.

Microbiology spectrum - 31 Aug 2022

Cheng Zetao, Yan Huanchang, Li Qingmei, Ablan Sherimay D, Kleinpeter Alex, Freed Eric O, Wu Hao, Dzakah Emmanuel Enoch, Zhao Jianhui, Han Zhigang, Wang Haiying, Tang Shixing

Abstract excerpt

HIV-1 CRF07_BC is one of the most common circulating recombinant forms (CRFs) in China and is becoming increasingly prevalent especially in HIV-infected men who have sex with men (MSM). The reason why this strain expanded so quickly in China remains to be defined. We previously observed that individuals infected with HIV-1 CRF07_BC showed slower disease progression than those infected with HIV-1 subtype B or...

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Identifiers

PMID: 35727067
DOI: 10.1128/spectrum.00146-22
PMCID: PMC9431131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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