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Article

Microdeletions and vertical transmission of the Y-chromosome azoospermia factor region

8 Mar 2022

Abstract excerpt

Spermatogenesis is regulated by several Y chromosome-specific genes located in a specific region of the long arm of the Y chromosome, the azoospermia factor region (AZF). AZF microdeletions are the main structural chromosomal abnormalities that cause male infertility. Assisted reproductive technology (ART) has been used to overcome natural fertilization barriers, allowing infertile couples to have children....

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PMID: 35259786
DOI: 10.4103/aja2021130

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