Article
Challenges in breast cancer genetic testing. A call for novel forms of multidisciplinary care and long-term evaluation.
Critical reviews in oncology/hematology - 1 Aug 2022
Menko Fred H, Monkhorst Kim, Hogervorst Frans B L, Rosenberg Efraim H, Adank Muriel A, Ruijs Mariëlle W G, Bleiker Eveline M A, Sonke Gabe S, Russell Nicola S, Oldenburg Hester S A, van der Kolk Lizet E
Abstract excerpt
Current methods of next generation sequencing may simultaneously detect multiple germline breast cancer susceptibility variants. However, it is a challenge to maximize the clinical benefit of genetic analysis for patients and family members while minimizing potentially harmful effects. Relevant issues include criteria for referral, the choice of gene panel, handling of variants of unknown significance, cancer...
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