Article
Application of a VP4/VP2-inferred transmission clusters in estimating the impact of interventions on rhinovirus transmission.
Virology journal - 4 Mar 2022
Ng Kim Tien, Ng Liang Jie, Oong Xiang Yong, Chook Jack Bee, Chan Kok Gan, Takebe Yutaka, Kamarulzaman Adeeba, Tee Kok Keng
Abstract excerpt
BACKGROUND: Despite the clinical burden attributable to rhinovirus (RV) infections, the RV transmission dynamics and the impact of interventions on viral transmission remain elusive. METHODS: A total of 3,935 nasopharyngeal specimens were examined, from which the VP4/VP2 gene was sequenced and genotyped. RV transmission clusters were reconstructed using the genetic threshold of 0.005 substitutions/site, estimated...
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