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Comprehensive Analysis of Immune Implications and Prognostic Value of SPI1 in Gastric Cancer

14 Feb 2022

Abstract excerpt

BACKGROUND: The transcription factor Spi-1 proto-oncogene (SPI1, also known as PU.1) is a key regulator of signal communication in the immune system and is essential for the development of myeloid cells and lymphocytes. However, the potential role of SPI1 in gastric cancer (GC) and the correlations between SPI1 and immune infiltration remain unclear. METHODS: in GC. cBioPortal was used to explore the possible...

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PMID: 35237521
DOI: 10.3389/fonc.2022.820568

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