Article
The Runaway Evolution of SARS-CoV-2 Leading to the Highly Evolved Delta Strain.
Molecular biology and evolution - 2 Mar 2022
Ruan Yongsen, Hou Mei, Tang Xiaolu, He Xionglei, Lu Xuemei, Lu Jian, Wu Chung-I, Wen Haijun
Abstract excerpt
In new epidemics after the host shift, the pathogens may experience accelerated evolution driven by novel selective pressures. When the accelerated evolution enters a positive feedback loop with the expanding epidemics, the pathogen's runaway evolution may be triggered. To test this possibility in coronavirus disease 2019 (COVID-19), we analyze the extensive databases and identify five major waves of strains, one...
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