Article
Prevalence of BCR-ABL T315I Mutation in Different Chronic Myeloid Leukemia patients Categories.
Pakistan journal of biological sciences : PJBS - 1 Jan 2022
Elsir Khair Hala, Ahmed Mohamed Babker, Yousef Nour Bakri, Ali Waggiallah Hisham
Abstract excerpt
<b>Background and Objective:</b> Chronic Myelogenous Leukaemia (CML) is a clonal myeloproliferative tumor distinguished by the existence of the Philadelphia chromosome (Ph) resulting from the t (9, 22) (q34, q11) translocation. The BCR-ABL gene and the fusion protein, which has constitutive tyrosine kinase activity, are the outcome of this translocation. The purpose of this study is to determine the...
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