Article
Deep learning based on biologically interpretable genome representation predicts two types of human adaptation of SARS-CoV-2 variants.
Briefings in bioinformatics - 13 May 2022
Li Jing, Wu Ya-Nan, Zhang Sen, Kang Xiao-Ping, Jiang Tao
Abstract excerpt
Explosively emerging SARS-CoV-2 variants challenge current nomenclature schemes based on genetic diversity and biological significance. Genomic composition-based machine learning methods have recently performed well in identifying phenotype-genotype relationships. We introduced a framework involving dinucleotide (DNT) composition representation (DCR) to parse the general human adaptation of RNA viruses and...
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