Article
Analysis of serum microRNAs and rs2910164 GC single-nucleotide polymorphism of miRNA-146a in COVID-19 patients.
Journal of immunoassay & immunochemistry - 4 Jul 2022
Pinacchio Claudia, Scordio Mirko, Santinelli Letizia, Frasca Federica, Sorrentino Leonardo, Bitossi Camilla, Oliveto Giuseppe, Viscido Agnese, Ceci Flavio Maria, Celani Luigi, Ceccarelli Giancarlo, Antonelli Guido, Mastroianni Claudio Maria, d'Ettorre Gabriella, Scagnolari Carolina
Abstract excerpt
Alteration of micro-RNAs (miRNAs) expression, including miRNA-122a, -146a and -205 family members, can have profound effects on inflammatory and IFN pathways (miRNA-146a), known as hallmarks of COVID-19. SARS-CoV-2-infected patients were recruited at Policlinico Umberto I Hospital of Sapienza University of Rome (Italy). MiRNA-122a, -146a, -205 and IFI27 (Interferon Alpha Inducible Protein 27) levels were screened...
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