Article
Can double PPO mutations exist in the same allele and are such mutants functional?
Pest management science - 1 Jun 2022
Porri Aimone, Noguera Matheus M, Betz Michael, Sälinger Daniel, Brändle Frank, Bowe Steven J, Lerchl Jens, Meyer Lucie, Knapp Michael, Roma-Burgos Nilda
Abstract excerpt
BACKGROUND: Resistance to protoporphyrinogen oxidase (PPO)-inhibiting herbicides is endowed primarily by target-site mutations at the PPX2 gene that compromise binding of the herbicide to the catalytic domain. In Amaranthus spp. PPX2, the most prevalent target mutations are deletion of the G210 codon, and the R128G and G339A substitutions. These mutations strongly affect the dynamic of the PPO2 binding pocket,...
Topics
- Alleles
- Amaranthus
- Escherichia coli
- Herbicide Resistance
- Herbicides
- Mutation
- Protoporphyrinogen Oxidase