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Article

Unraveling Gut Microbiota Signatures Associated with PPARD and PARGC1A Genetic Polymorphisms in a Healthy Population.

Genes - 1 Feb 2022

Bailén María, Tabone Mariangela, Bressa Carlo, Lominchar María Gregoria Montalvo, Larrosa Mar, González-Soltero Rocío

Abstract excerpt

Recent studies have revealed the importance of the gut microbiota in the regulation of metabolic phenotypes of highly prevalent metabolic diseases such as obesity, type II diabetes mellitus (T2DM) and cardiovascular disease. Peroxisome proliferator-activated receptors (PPARs) are a family of ligand-activated nuclear receptors that interact with PPAR-γ co-activator-1α (PPARGC1A) to regulate lipid and glucose...

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Source

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Identifiers

PMID: 35205333
DOI: 10.3390/genes13020289
PMCID: PMC8871880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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