Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Asymptomatic Hyperuricemia Promotes Recovery from Ischemic Organ Injury by Modulating the Phenotype of Macrophages.

Cells - 11 Feb 2022

Gnemmi Viviane, Li Qiubo, Ma Qiuyue, De Chiara Letizia, Carangelo Giulia, Li Chenyu, Molina-Van den Bosch Mireia, Romagnani Paola, Anders Hans-Joachim, Steiger Stefanie

Abstract excerpt

Acute organ injury, such as acute kidney injury (AKI) and disease (AKD), are major causes of morbidity and mortality worldwide. Hyperuricemia (HU) is common in patients with impaired kidney function but the impact of asymptomatic HU on the different phases of AKI/AKD is incompletely understood. We hypothesized that asymptomatic HU would attenuate AKD because soluble, in contrast to crystalline, uric acid (sUA)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hyperuricemia
Share to Acute Kidney Injury

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation

Share to Ischemia

Share to Macrophages

Share to Reperfusion Injury

Share to Uric Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 35203277
DOI: 10.3390/cells11040626
PMCID: PMC8869798

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Asymptomatic Hyperuricemia Promotes Recovery from Ischemic Organ Injury by Modulating the Phenotype of Macrophages.PMID 35203277Read ↗

Insights into renal damage in hyperuricemia: Focus on renal protection (Review)Semantic proximity Read ↗

Hyperuricemia causes kidney damage by promoting autophagy and NLRP3-mediated inflammation in rats with urate oxidase deficiencySemantic proximity Read ↗

Hyperuricemia and its related diseases: mechanisms and advances in therapySemantic proximity Read ↗

[Hyperuricemic nephropathy: Pathogenesis, pathophysiology, and therapy].Semantic proximity Read ↗

Aristolochic acid I determine the phenotype and activation of macrophages in acute and chronic kidney disease.Semantic proximity Read ↗

Serum Amino Acid Alterations in Hyperuricemia: Potential Targets for Renal Disease PreventionSemantic proximity Read ↗

Navigating the Complex Pathogenesis of Acute Kidney Injury: Exploring Macrophage Dynamics, Mitochondrial Dysfunction, and Ferroptosis PathwaysSemantic proximity Read ↗

The role of macrophages during acute kidney injury: destruction and repair.Semantic proximity Read ↗

Pathogenic and protective role of macrophages in kidney disease.Semantic proximity Read ↗

CRISPR/Cas9 Mediated Deletion of the Uox Gene Generates a Mouse Model of Hyperuricemia with Multiple Complications.Semantic proximity Read ↗

Complex Pathophysiology of Acute Kidney Injury (AKI) in Aging: Epigenetic Regulation, Matrix Remodeling, and the Healing Effects of H2SSemantic proximity Read ↗

The renoprotective and anti-inflammatory effects of human urine-derived stem cells in acute kidney injury animalsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.