Article
Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies.
Transfusion - 1 May 2022
Gajic-Veljanoski Olga, Li Chunmei, Schaink Alexis K, Guo Jennifer, Shehata Nadine, Charames George S, de Vrijer Barbra, Clarke Gwen, Pechlivanoglou Petros, Okun Nanette, Kandel Rita, Dooley Joseph, Higgins Caroline, Ng Vivian, Sikich Nancy
Abstract excerpt
BACKGROUND: We sought to determine the cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies in Canada. STUDY DESIGN AND METHODS: We developed two probabilistic state-transition (Markov) microsimulation models to compare fetal genotyping followed by targeted management versus usual care (i.e., universal Rh immunoglobulin [RhIG] prophylaxis in...
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