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Article

Club cell 10-kDa protein (CC10) as a surrogate for identifying type 2 asthma phenotypes.

The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Jan 2023

Wang Meijia, Tang Kun, Gao Pengfei, Lu Yanjiao, Wang Shanshan, Wu Xiaojie, Zhao Jianping, Xie Jungang

Abstract excerpt

Club cell 10-kDa protein (CC10) is a documented biomarker for airway obstructive diseases. Primarily produced by nonciliated club cells in the distal airway and in nasal epithelial cells, CC10 suppresses Th2 cell differentiation and Th2 cytokine production. In this study, we aimed to determine whether CC10 can also be used as an alternative biomarker for identifying Type 2 (T2) asthma. 74 patients with asthma,...

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PMID: 35168451
DOI: 10.1080/02770903.2022.2040531

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