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The Potential Role of Spermine and Its Acetylated Derivative in Human Malignancies

23 Jan 2022

Abstract excerpt

Polyamines are essential biomolecules for normal cellular metabolism in humans. The roles of polyamines in cancer development have been widely discussed in recent years. Among all, spermine alongside with its acetylated derivative, N1, N12-Diacetylspermine, demonstrate a relationship with the diagnosis and staging of various cancers, including lung, breast, liver, colorectal and urogenital. Numerous studies have...

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PMID: 35163181
DOI: 10.3390/ijms23031258

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