Article
Recurrent KRAS mutations are early events in the development of papillary renal neoplasm with reverse polarity.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2022
Al-Obaidy Khaleel I, Saleeb Rola M, Trpkov Kiril, Williamson Sean R, Sangoi Ankur R, Nassiri Mehdi, Hes Ondrej, Montironi Rodolfo, Cimadamore Alessia, Acosta Andres M, Alruwaii Zainab I, Alkashash Ahmad, Hassan Oudai, Gupta Nilesh, Osunkoya Adeboye O, Sen Joyashree D, Baldrige Lee Ann, Sakr Wael A, Idrees Muhammad T, Eble John N, Grignon David J, Cheng Liang
Abstract excerpt
We evaluated the clinicopathologic and molecular characteristics of mostly incidentally detected, small, papillary renal neoplasms with reverse polarity (PRNRP). The cohort comprised 50 PRNRP from 46 patients, divided into 2 groups. The clinically undetected (<5 mm) neoplasms (n = 34; 68%) had a median size of 1.1 mm (range 0.2-4.3 mm; mean 1.4 mm), and the clinically detected (≥5 mm) neoplasms (n = 16; 32%)...
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