Article
Gamma distribution model of diffusion MRI for evaluating the isocitrate dehydrogenase mutation status of glioblastomas.
The British journal of radiology - 1 May 2022
Takase Hanae, Togao Osamu, Kikuchi Kazufumi, Hata Nobuhiro, Hatae Ryusuke, Chikui Toru, Tokumori Kenji, Kami Yukiko, Kuga Daisuke, Sangatsuda Yuhei, Mizoguchi Masahiro, Hiwatashi Akio, Ishigami Kousei
Abstract excerpt
OBJECTIVE: To determine whether the γ distribution (GD) model of diffusion MRI is useful in the evaluation of the isocitrate dehydrogenase (IDH) mutation status of glioblastomas. METHODS: 12 patients with IDH-mutant glioblastomas and 54 patients with IDH-wildtype glioblastomas were imaged with diffusion-weighted imaging using 13 b-values from 0 to 1000 s/mm2. The shape parameter (κ) and scale parameter (θ) were...
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