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The Anticancer Agent 3,3'-Diindolylmethane Inhibits Multispecies Biofilm Formation by Acne-Causing Bacteria and Candida albicans

2 Feb 2022

Abstract excerpt

Since indoles are widespread in nature (even in human skin), we hypothesized that indole and its derivatives might control biofilm formation of acne-causing bacteria ( Cutibacterium acnes and Staphylococcus aureus ) and fungal Candida albicans . The present study reports for the first time the antibiofilm and antimicrobial activities of several indoles on C. acnes .

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Share to Antifungal resistance and susceptibility
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PMID: 35107361
DOI: 10.1128/spectrum.02056-21

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