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Vaccines elicit highly conserved cellular immunity to SARS-CoV-2 Omicron

31 Jan 2022

Abstract excerpt

Abstract The highly mutated SARS-CoV-2 Omicron (B.1.1.529) variant has been shown to evade a substantial fraction of neutralizing antibody responses elicited by current vaccines that encode the WA1/2020 spike protein 1 . Cellular immune responses, particularly CD8 + T cell responses, probably contribute to protection against severe SARS-CoV-2 infection 2–6 . Here we show that cellular immunity induced by current...

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PMID: 35102312
DOI: 10.1038/s41586-022-04465-y

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