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Article

The Application of Whole-Exome Sequencing in Patients With FUO.

Frontiers in cellular and infection microbiology - 1 Jan 2021

Guo Wanru, Feng Xuewen, Hu Ming, Shangguan Yanwan, Xia Jiafeng, Hu Wenjuan, Li Xiaomeng, Zhang Zunjing, Shi Yunzhen, Xu Kaijin

Abstract excerpt

BACKGROUND: Fever of unknown origin (FUO) is still a challenge for clinicians. Next-generation sequencing technologies, such as whole exome sequencing (WES), can be used to identify genetic defects in patients and assist in diagnosis. In this study, we investigated the application of WES in individuals with FUO. METHODS: We performed whole-exome sequencing on 15 FUO patients. Clinical information was extracted...

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Identifiers

PMID: 35096640
DOI: 10.3389/fcimb.2021.783568
PMCID: PMC8790153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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