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Article

Comparison of acute myeloid leukemia and myelodysplastic syndromes with TP53 aberrations.

Annals of hematology - 1 Apr 2022

Dutta Sayantanee, Moritz Jennifer, Pregartner Gudrun, Thallinger Gerhard G, Brandstätter Ilona, Lind Karin, Rezania Simin, Lyssy Freya, Reinisch Andreas, Zebisch Armin, Berghold Andrea, Wölfler Albert, Sill Heinz

Abstract excerpt

TP53 aberrations are found in approximately 10% of patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) and are considered early driver events affecting leukemia stem cells. In this study, we compared features of a total of 84 patients with these disorders seen at a tertiary cancer center. Clinical and cytogenetic characteristics as well as immunophenotypes of immature blast cells were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35083527
DOI: 10.1007/s00277-022-04766-2
PMCID: PMC8913568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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