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Article

Combination of target site mutation and associated CYPs confers high-level resistance to pyridaben in Tetranychus urticae.

Pesticide biochemistry and physiology - 1 Feb 2022

Itoh Yusuke, Shimotsuma Yushi, Jouraku Akiya, Dermauw Wannes, Van Leeuwen Thomas, Osakabe Masahiro

Abstract excerpt

Pyridaben is a mitochondrial electron transport complex I inhibitor. The H110R mutation in the PSST subunit has been reported as a major factor in pyridaben resistance in the two-spotted spider mite, Tetranychus urticae. However, backcross experiments revealed that the mutant PSST alone conferred only moderate resistance. In contrast, inhibition of cytochrome P450 (CYP) markedly reduces resistance levels in a...

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Identifiers

PMID: 35082027
DOI: 10.1016/j.pestbp.2021.105000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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