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Sex differences in microRNA expression in first and third trimester human placenta

7 Dec 2021

Abstract excerpt

Maternal and fetal pregnancy outcomes related to placental function vary based on fetal sex, which may be due to sexually dimorphic epigenetic regulation of RNA expression. We identified sexually dimorphic miRNA expression throughout gestation in human placentae. Next-generation sequencing identified miRNA expression profiles in first and third trimester uncomplicated pregnancies using tissue obtained at...

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PMID: 35040930
DOI: 10.1093/biolre/ioab221

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